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What role does High-Density Lipoprotein (HDL) play in the body?

  1. Transfers glucose to muscles

  2. Carries excess cholesterol from arteries to liver

  3. Stores fat in adipose tissue

  4. Increases blood sugar levels

The correct answer is: Carries excess cholesterol from arteries to liver

High-Density Lipoprotein (HDL) is often referred to as "good cholesterol" because of its essential role in the body's lipid metabolism. It primarily functions to transport excess cholesterol from the arteries and other tissues back to the liver for processing and excretion. This mechanism helps to reduce the risk of atherosclerosis, which is the buildup of cholesterol and other substances in the arterial walls that can lead to cardiovascular diseases. The ability of HDL to carry cholesterol away from the arteries is critical for maintaining cardiovascular health. By facilitating the return of cholesterol to the liver, HDL helps to prevent the accumulation of plaque within blood vessels, thereby promoting better blood flow and reducing the likelihood of heart disease and stroke. In contrast, the other choices do not accurately reflect the role of HDL. For instance, the transfer of glucose to muscles is not related to HDL but rather involves insulin and other hormones. Storing fat in adipose tissue is a function associated with various forms of lipoproteins but not specifically with HDL. Increasing blood sugar levels is also unrelated, as HDL's primary function revolves around cholesterol transport, not glucose metabolism. Thus, the role of HDL as a carrier for excess cholesterol to the liver is crucial for understanding its importance in overall health.